Drago L, Iemoli E, Rodighiero V, Nicola L, De Vecchi E, Piconi S. Effects of Lactobacillus salivarius LS01 (DSM 22775) treatment on adult atopic dermatitis: A randomized placebo-controlled study. Int J Immunopathol Pharmacol. 2011;24(4):1037-1048. doi:10.1177/039463201102400421 Highly researchedContains the world-renowned live cultures strain, B. breve M-16V®, researched in thousands of babies and children in gold standard clinical trials Abuabara K, Ye M, McCulloch CE, et al. Clinical onset of atopic eczema: Results from 2 nationally representative British birth cohorts followed through midlife. J Allergy Clin Immunol. 2019;144(3):710-719. doi:10.1016/j.jaci.2019.05.040

Mansfield JA, Bergin SW, Cooper JR, Olsen CH. Comparative Probiotic Strain Efficacy in the Prevention of Eczema in Infants and Children: A Systematic Review and Meta-Analysis. Mil Med. 2014;179(6):580-592. doi:10.7205/milmed-d-13-00546 Makrgeorgou A, Leonardi-Bee J, Bath-Hextall FJ, et al. Probiotics for treating eczema.Cochrane Database Syst Rev. 2018;2018(11). doi:10.1002/14651858.CD006135.pub3 Healthcare professionals can visit the Probiotics Database to read more about the research behind Lactobacillus rhamnosus HN001 ®, Lactobacillus rhamnosus GG ®, Bifidobacteriumlactis BB-12 ®, Bifidobacteriumbreve M-16V ®and Bifidobacteriumlactis Bi-07 . References

Friendly bacteria: your questions answered

In today’s world, eczema is a very common and unpleasant complaint. The gut microbiome has become increasingly recognised for its role in inflammatory and immune-mediated conditions, including eczema.Dysbiosis has been identified in many of those who suffer with eczema 1. Probiotics for eczema and thegut microbiome with probiotics is a growing area of interest to help manage symptoms. Read more about this on the Probiotics Learning Lab: What are Probiotics? We know that this is coming to you during a very surreal time. Parents have been asking for a friendlier format of live cultures for their little ones for a long time and this product has been years in the making. We know this isn’t a big fix for you right now, in the grand scheme of things, but it might help in some small way to navigate some of the more minor problems parents are facing as family life goes on. We know that every child is different, so we’ve tried to make our newest supplement as inclusive as possible. It’s clinically trialled and proven to be safe from birth. What’s more, it’s vegan, gluten free, and doesn’t contain any artificial flavours, colours or preservatives. Which supplement is best for my child?

Nummular or Discoid Dermatitis (inflammatory eczema triggered by environmental triggers, characteristic discoid shape) Most trusted by parentsOptibac is the brand of friendly bacteria supplements most trusted by parents in the UK

Not sure which supplement is best for your children?

Award-winninglive cultures supplement for babiesWinner of 2020 National Parenting Product Awards and Nutra Ingredients Asia Award 2019 for Ingredient of the Year: Infant Nutrition In early life, colonisation of the gut with microbes is fundamental for the development of a healthy immune system. These microbes activate and promote healthy development of the immature gut mucosal immune system. The hygiene hypothesis identifies an association between the increasing prevalence of atopic and allergic conditions and features of a typical Western lifestyle including highly sanitised environments and antibiotic exposure 9. Infants are exposed to microbes in their environment less and less which can prevent adequate development of the immune system. An immature immune system is dominated by a T helper 2 cell immune response which is implicated in allergic and atopic diseases including atopic dermatitis. For more information about the gut microbiome in early life, read this article on how the infant gut develops. How can probiotics for eczema help? Antibiotics are known to deplete our natural friendly bacteria populations. Interestingly, the use of antibiotics in the first 2 years of life has been associated with an increased risk of developing eczema 10 , 11. Replenishing the gut microbiome with specific probiotic bacteria while taking an antibiotic is a worthwhile endeavour. To learn more, read this article about taking probiotics with antibiotics. Winner of 2020 National Parenting Product Awards and Nutra Ingredients Asia Award 2019 for Ingredient of the Year: Infant Nutrition Species of bacteria that may be useful include various strains of Lactobacilli such as Lactobacillus rhamnosus HN001 ®, Bifidobacteriumbreve M-16V ®, Bifidobacteriumlactis Bi-07 and Lactobacillus salivarius LS01.

Easy-to-use dropper - administer directly into baby’s mouth*, on a spoon or mix into cool milk or food Based on this research, health professionals may like to consider gut health and probiotic supplementation as part of any supporting protocol for eczema. All questions answered by probiotic expert Kerry Beeson BSc (Nut. Med.) Nutritional Therapist. What are baby live cultures? You might already have seen our other children’s supplement, ‘ For babies & children’ and indeed there is some overlap here - in that either of these products could be applicable. So, how do you know which is the best for your little one? We've put together some bullet points to help guide you.

Tại sao nên chọn Optibac Probiotics?

This article looks at the different types of eczema, and the way in which probiotics might help as part of a management protocol: Lopetuso LR. The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors. 2015;(19):1068-1076. The term eczema refers to a group of inflammatory skin conditions. There are many different types of eczema, categorised based on the underlying cause and skin location affected 2. The lifetime prevalence of eczema is reported to be 28% of the population, but it is most common in children. Up to 20% of children are affected 3, with 60% of cases developing before the age of one year. For most individuals, it resolves in adolescence. There is often a predisposition for the development of other atopic diseases such as asthma and allergic rhinitis, known as the “atopic march” 3. Read more about recent clinical research behind probiotics for asthma .

A more natural optionVegan and gluten free, and absolutely no added sugars, artificial flavours or colours Optibac are the UK's most recommended friendly bacteria supplements. Their specialised strains of friendly bacteria are scientifically proven to reach the gut alive. They are at the forefront of using specific strains for individual needs, recognising that when it comes to live cultures it's not a question of one size fits all. Atopic dermatitis is the most common type of eczema. It is a chronic inflammatory skin condition which can affect all age groups. For your baby' has more research in babies and toddlers, whereas 'For babies & children' has more research in school-aged children. For your baby’ is a daily baby drops supplement and contains the friendly bacteria strain Bifidobacterium breve M-16V®, which is new to the Optibacrange. This strain has been extensively researched in over 4,000 infants and young children, and featured in over 36 clinical trials in which it was shownto support skin and immune health in very young children. This super probiotic strain has also been shown to increase levels offriendly Bifidobacteria in the gut, andreduce the growth ofbad bacteriaoften associated with the development of colic. It is proven to be safe for use in infants, and isused in neonatal intensive care units around the world.In a double blind randomised controlled trial of 38 adults with moderate to severe atopic dermatitis, 19 participants were allocated to receive 2 billion CFU of L. salivarius LS01 per day for 4 months and the others were given a placebo 22. A significant improvement in the probiotic group was noted after 8 weeks in comparison with placebo (p<0.001). The presence of Staphylococcus was significantly reduced in the probiotic group compared with placebo (p<0.05). Although the probiotic group achieved better results than the placebo group, the results of the placebo group were also significantly improved from baseline. Further clinical testing is required to assess the effects of this strain. Flavourless liquid drops formulaEasy-to-use baby friendly bacteria drops; can be administered directly into baby’s mouth*, on a spoon or mixed into cool milk or food